| 1921 Louisville Brecks season | |
|---|---|
| Head coach | Austin Higgins |
| Home field | Eclipse Park |
| Results | |
| Record | 4–4–1 Overall 0–2 APFA |
| League place | T-18th APFA |
The 1921 Louisville Brecks season was their inaugural season in the National Football League. The team finished 0–2 against league teams, and tied for eighteenth place in the league.
Note: Tie games were not officially counted in the standings until 1972.