| 1978 Monte Carlo Open | |
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| Date | 10 – 16 April |
| Edition | 72nd |
| Category | Grand Prix circuit (WCT) |
| Draw | 32S/16D |
| Prize money | $175,000 |
| Surface | Clay / outdoor |
| Location | Monte Carlo, Monaco |
| Venue | Monte Carlo Country Club |
| Champions | |
| Singles | |
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| Doubles | |
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The 1978 Monte Carlo Open was a men's tennis tournament played on outdoor clay courts at the Monte Carlo Country Club in Monte Carlo, Monaco . The tournament was part of the WCT Tour, which was incorporated into the 1978 Colgate-Palmolive Grand Prix circuit. It was the 72nd edition of the event and was held from 10 April through 16 April 1978. Raúl Ramírez, the no. 5 seed, won the singles title.
Raúl Ramírez defeated
Tomáš Šmíd 6–3, 6–3, 6–4
Peter Fleming /
Tomáš Šmíd defeated
Jaime Fillol /
Ilie Năstase 6–4, 7–5