| Country | England & |
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| Teams | 92 | ||
| Champions | Liverpool | ||
| Runners-up | West Ham United | ||
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| Event | 1980–81 Football League Cup | ||||||
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| Date | 14 March 1981 | ||||||
| Venue | Wembley Stadium, London | ||||||
| Referee | Clive Thomas (Treorchy) | ||||||
| Attendance | 100,000 | ||||||
| Replay | |||||||
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| Date | 1 April 1981 | ||||||
| Venue | Villa Park, Birmingham | ||||||
| Referee | Clive Thomas (Treorchy) | ||||||
| Attendance | 36,693 | ||||||
The 1980–81 Football League Cup was the twenty-first season of the Football League Cup, a knockout competition for England's top 92 football clubs. The competition started on 8 August 1980 and ended with the final replay on 1 April 1981.
The final was contested by First Division team Liverpool and Second Division West Ham United at Wembley Stadium in London and replayed at Villa Park.