The 1981 Grand Marnier Tennis Games was a men's professional tennis tournament played on outdoor hard courts. It was the 6th edition of the Indian Wells Masters and was part of the 1981 Volvo Grand Prix. It was played at the La Quinta Resort and Club in La Quinta, California in the United States and was held from February 16 through February 22, 1981.

Jimmy Connors defeated Ivan Lendl 6–3, 7–6

Bruce Manson / Brian Teacher defeated Terry Moor / Eliot Teltscher 7–6, 6–2