The 1988 World Series matched the Oakland Athletics against the Los Angeles Dodgers, with the Dodgers upsetting the heavily favored A's to win the Series in five games. It is best known for the pinch-hit walk-off home run hit by Dodgers MVP Kirk Gibson, who could barely walk due to injuries suffered during the NLCS, against Hall-of-Fame Athletics closer Dennis Eckersley in Game 1.

Although Gibson's home run has become an icon of baseball, it was series MVP Orel Hershiser who capped a dominant 1988 season in which he set the all time scoreless inning streak at 59 innings, recorded five straight shutouts, led the league with 23 wins and 267 innings, and won the Cy Young and Gold Glove awards. Hershiser was the MVP of the NLCS, starting three games, getting the save for Game 4, and shutting out the Mets in Game 7. In the World Series, he shut out the heavily favored A's in Game 2, and pitched a two-run, complete game in the decisive Game 5 victory.

The Los Angeles Dodgers won the National League West division by seven games over the Cincinnati Reds then upset the New York Mets, four games to three, in the 1988 NLCS. The Oakland Athletics won the American League West division by thirteen games over the Minnesota Twins then swept the Boston Red Sox, four games to none, in the American League Championship Series. This was the first World Series to have the series logo on the players' uniforms of both teams (the previous year, only the Cardinals wore it).

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