20α-Hydroxyprogesterone

20α-Dihydroprogesterone
Identifiers


CAS Number	145-14-2^Y[yes]
3D model (JSmol)	Interactive image
ChemSpider	83725
ECHA InfoCard	100.005.136
EC Number	205-649-5
MeSH	20-alpha-Dihydroprogesterone
PubChem CID	8956
UNII	45630A64AC^Y
InChI InChI=1/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16+,17-,18+,19+,20+,21-/m1/s1 Key: RWBRUCCWZPSBFC-SJOKZOANBK
SMILES O=C4\C=C2/[C@]([C@H]1CC[C@@]3([C@H](CC[C@H]3[C@@H]1CC2)[C@H](O)C)C)(C)CC4
Properties
Chemical formula	C₂₁H₃₂O₂
Molar mass	316.478 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y (what is ^YN ?)
Infobox references

20α-Dihydroprogesterone (20α-DHP), also known as 20α-hydroxyprogesterone (20α-OHP), is a naturally occurring, endogenous progestogen. It is a metabolite of progesterone, converted by the 20α-hydroxysteroid dehydrogenases AKR1C1 and AKR1C3, and although still active as a progestogen, is much less potent in comparison. It has been found to act as an aromatase inhibitor and to inhibit the production of estrogen in breast tissue in vitro.