| Country |
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|---|---|---|---|
| Teams | 30 | ||
| Champions | Marino Luanco | ||
| Runners-up | Tropezón | ||
|
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The Copa Federación de España 2000–01 was the 8th staging of the Copa Federación de España, a knockout competition for Spanish football clubs in Segunda División B and Tercera División.
The Regional stages began in 2000, while the national tournament took place from November 2000 to April 2001.