| Singles | |
|---|---|
| 2001 IGA U.S. Indoor Championships | |
| 2000 Champion |
|
| Champion |
|
| Runner-up |
|
| Final score | 6–3, 5–7, 6–2 |
Monica Seles was the defending champion and won in the final 6–3, 5–7, 6–2 against Jennifer Capriati.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated. The top two seeds received a bye to the second round.