| Women's Singles | |
|---|---|
| 2005 Internazionali BNL d'Italia | |
| Champion |
|
| Runner-up |
|
| Final score | 2–6, 6–3, 6–4 |
Amélie Mauresmo was the defending champion and successfully defended her title, defeating Patty Schnyder 2–6, 6–3, 6–4 in the final.
The first eight seeds received a bye into the second round.