| Women's Singles | |
|---|---|
| 2006 ECM Prague Open | |
| Champion |
|
| Runner-up |
|
| Final score | 4–6, 6–2, 6–1 |
Dinara Safina was the defending champion, but competed in Berlin at the same week.
Shahar Pe'er won the title by defeating Samantha Stosur 4–6, 6–2, 6–1 in the final.