| Singles | |
|---|---|
| 2008 U.S. Men's Clay Court Championships | |
| Champion |
|
| Runner-up |
|
| Final score | 6–4, 1–6, 7–5 |
| Draw | 32 (4Q / 3WC) |
| Seeds | 8 |
Ivo Karlović was the defending champion, but chose not to participate that year.
Seventh-seeded Marcel Granollers-Pujol won in the final 6–4, 1–6, 7–5, against James Blake.