2010 Challenger Ciudad de Guayaquil – Singles
| Singles | |
|---|---|
| 2010 Challenger Ciudad de Guayaquil | |
| Champion |
 Paul Capdeville
|
| Runner-up |
 Diego Junqueira
|
| Final score | 6–3, 3–6, 6–3 |
Nicolás Lapentti was the defending champion; however, he retired from professional tennis before this tournament.
Paul Capdeville won the title, defeating Diego Junqueira 6–3, 3–6, 6–3 in the final.
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