The 2010 FC Anzhi Makhachkala season was the 1st season that the club played in the Russian Premier League, the highest tier of football in Russia since their relegation in 2002. They finished 11th in the league and also took part in the 2010–11 Russian Cup, exiting at the round of 16 stage.

Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Reserves are eligible to play in the league.

Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

In: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Out: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

In: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Out: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Last updated: 5 June 2013.
Source: Russian Premier League
Ground: A = Away; H = Home. Result: D = Draw; L = Loss; W = Win; P = Postponed.

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