| 2010 Open Castilla y León | |
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| Date | August 2 – August 8 |
| Edition | 25th |
| Location | Segovia, Spain |
| Champions | |
| Singles | |
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| Doubles | |
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The 2010 Open Castilla y León was a professional tennis tournament played on outdoor hard courts. It was the twenty fifth edition of the tournament which was part of the Tretorn SERIE+ of the 2010 ATP Challenger Tour. It took place in Segovia, Spain between 2 and 8 August 2010.
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Daniel Gimeno-Traver def.
Adrian Mannarino, 6–4, 7–6(2)
Thiago Alves /
Franco Ferreiro def.
Brian Battistone /
Harsh Mankad, 6–2, 5–7, [10–8]