| Singles | |
|---|---|
| 2012 Internazionali Femminili di Palermo | |
| Champion |
|
| Runner-up |
|
| Final score | 6–1, 6–3 |
Anabel Medina Garrigues was the defending champion, but lost to Maria Elena Camerin in the first round.
Top seed Sara Errani won the title by beating Barbora Záhlavová-Strýcová 6–1, 6–3 in the final. She did not drop a set the entire tournament.