| Singles | |
|---|---|
| 2012 New Haven Open at Yale | |
| Champion |
|
| Runner-up |
|
| Final score | 7–6(11–9), 7–5 |
Caroline Wozniacki was the four-time defending champion. She retired in the semifinals against Maria Kirilenko.
Petra Kvitová defeated Kirilenko 7–6(11–9), 7–5 in the final.
The top two seeds receive a bye into the second round.