| Singles | |
|---|---|
| 2012 Serbia Open | |
| Champion |
|
| Runner-up |
|
| Final score | 6–3, 6–2 |
Novak Djokovic was the defending champion, but decided not to participate.
Andreas Seppi won the title defeating Benoît Paire 6–3, 6–2 in the final.
The top four seeds receive a bye into the second round.