| Women's Singles | |
|---|---|
| 2012 Western & Southern Open | |
| Champion |
|
| Runner-up |
|
| Final score | 1–6, 6–3, 6–1 |
Maria Sharapova was the defending champion, but withdrew because of a stomach virus.
Li Na defeated Angelique Kerber for the title, 1–6, 6–3, 6–1.
The top eight seeds and the Montreal finalists receive a bye into the second round.