| Singles | |
|---|---|
| 2013 Monte-Carlo Rolex Masters | |
| Champion |
|
| Runner-up |
|
| Final score | 6–2, 7–6(7–1) |
Rafael Nadal was the eight-time defending champion, but was defeated in the final by Novak Djokovic 2–6, 6–7(1–7), bringing an end to Nadal's 46-match winning streak at the event. As a result, Djokovic became the first man ever to win singles titles at 8 of the 9 Masters 1000 series tournaments.
The top eight seeds receive a bye into the second round.