| Wheelchair Women's Singles | |
|---|---|
| 2013 US Open | |
| Champion |
|
| Runner-up |
|
| Final score | 3-6, 6-2, 7-6(7-3) |
Esther Vergeer was the defending champion from 2011, since the event was not held in 2012 due to a schedule conflict with the 2012 Summer Paralympics. Vergeer retired earlier in the season.
Aniek van Koot won the title, defeating Sabine Ellerbrock 3-6, 6-2, 7-6 (7-3).