| Singles | |
|---|---|
| 2014 U.S. National Indoor Tennis Championships | |
| Champion |
|
| Runner-up |
|
| Final score | 6–4, 7–6(7–0) |
Kei Nishikori was the defending champion and successfully defended his title, defeating Ivo Karlović in the final, 6–4, 7–6(7–0).
The top four seeds receive a bye into the second round.