The 2015–16 season is FC Sheriff Tiraspol's 19th season, and their 18th in the Divizia Naţională, the top-flight of Moldovan football. Sheriff Tiraspol are the current defending champions of the Moldovan Cup, and were knocked out of the Europa League by Norwegian side Odds BK, whilst defeating FC Milsami Orhei in the Moldovan Super Cup.

Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

In: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Out: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

In: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Out: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Last updated: 31 May 2016.
Source: Soccerway