2015 Comerica Bank Challenger – Singles
| Singles | |
|---|---|
| 2015 Comerica Bank Challenger | |
| Champion |
 John Millman
|
| Runner-up |
 Austin Krajicek
|
| Final score | 7–5, 2–6, 6–3 |
Marcos Baghdatis was the defending champion but chose not to compete.
John Millman won the tournament, defeating Austin Krajicek in the final, 7–5, 2–6, 6–3.
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