2016 Brasil Open – Singles
| Singles | |
|---|---|
| 2016 Brasil Open | |
| Champion |
 Pablo Cuevas
|
| Runner-up |
 Pablo Carreño Busta
|
| Final score | 7–6(7–4), 6–3 |
Pablo Cuevas was the defending champion and successfully defended his title, defeating Pablo Carreño Busta in the final, 7–6(7–4), 6–3.
The top four seeds receive a bye into the second round.
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