| 2016 Engie Open de Cagnes-sur-Mer Alpes-Maritimes | |
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| Date | 2–8 May |
| Edition | 19th |
| Category | ITF Women's Circuit |
| Prize money | $100,000 |
| Surface | Clay |
| Location | Cagnes-sur-Mer, France |
| Champions | |
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The 2016 Engie Open de Cagnes-sur-Mer Alpes-Maritimes was a professional tennis tournament played on outdoor clay courts. It was the nineteenth edition of the tournament and part of the 2016 ITF Women's Circuit, offering a total of $100,000 in prize money. It took place in Cagnes-sur-Mer, France, on 2–8 May 2016.
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry by a lucky loser spot: