2016 Internazionali di Tennis Castel del Monte – Singles
| Singles | |
|---|---|
| 2016 Internazionali di Tennis Castel del Monte | |
| Champion |
 Luca Vanni
|
| Runner-up |
Matteo Berrettini
|
| Final score | 5–7, 6–0, 6–3 |
Ivan Dodig was the defending champion but chose not to defend his title.
Luca Vanni won the title after defeating Matteo Berrettini 5–7, 6–0, 6–3 in the final.
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