| Men's Singles | |
|---|---|
| 2016 Mutua Madrid Open | |
| Champion |
|
| Runner-up |
|
| Final score | 6–2, 3–6, 6–3 |
Andy Murray was the defending champion, but lost in the final to Novak Djokovic, 2–6, 6–3, 3–6.
The top eight seeds receive a bye into the second round.
Click on the seed number of a player to go to their draw section.