2016 Open de Nice Côte d'Azur – Singles
| Singles | |
|---|---|
| 2016 Open de Nice Côte d'Azur | |
| Champion |
 Dominic Thiem
|
| Runner-up |
 Alexander Zverev
|
| Final score | 6–4, 3–6, 6–0 |
Dominic Thiem was the defending champion and successfully defended his title, defeating Alexander Zverev in the final, 6–4, 3–6, 6–0.
The top four seeds receive a bye into the second round.
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