4E-BP1

EIF4EBP1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1EJ4, 1WKW, 2JGB, 2JGC, 2V8W, 2V8X, 2V8Y, 3HXG, 3HXI, 3M93, 3M94, 3U7X, 4UED, 5BXV

Identifiers

EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I, eukaryotic translation initiation factor 4E binding protein 1

External IDs

Gene ontology
Molecular function	• translation repressor activity • protein binding • eukaryotic initiation factor 4E binding • protein phosphatase 2A binding • translation initiation factor binding
Cellular component	• cytosol • protein complex • nucleus • cytoplasm
Biological process	• negative regulation of translation • negative regulation of translational initiation • lung development • G1/S transition of mitotic cell cycle • negative regulation of protein complex assembly • positive regulation of mitotic cell cycle • response to ischemia • TOR signaling • IRES-dependent translational initiation of linear mRNA • response to ethanol • cellular response to hypoxia • regulation of translation • response to amino acid starvation • insulin receptor signaling pathway • cellular response to dexamethasone stimulus
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


1978


13685


ENSG00000187840


ENSMUSG00000031490


Q13541


Q60876

RefSeq (mRNA)


NM_004095


NM_007918

RefSeq (protein)


NP_004086


NP_031944

Location (UCSC)

PubMed search