ACSL1

Identifiers

ACSL1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2, acyl-CoA synthetase long-chain family member 1, acyl-CoA synthetase long chain family member 1

External IDs

Gene ontology
Molecular function	• long-chain fatty acid-CoA ligase activity • nucleotide binding • ligase activity • catalytic activity • ATP binding • decanoate--CoA ligase activity
Cellular component	• organelle membrane • integral component of membrane • endoplasmic reticulum membrane • membrane • intracellular membrane-bounded organelle • plasma membrane • peroxisomal membrane • peroxisome • mitochondrial outer membrane • mitochondrion • endoplasmic reticulum
Biological process	• linoleic acid metabolic process • lipid biosynthetic process • xenobiotic catabolic process • response to organic cyclic compound • response to nutrient • lipid metabolic process • alpha-linolenic acid metabolic process • fatty acid transport • response to organic substance • adiponectin-activated signaling pathway • fatty acid metabolic process • positive regulation of protein serine/threonine kinase activity • long-chain fatty-acyl-CoA biosynthetic process • long-chain fatty acid import • metabolic process • long-chain fatty acid metabolic process • triglyceride metabolic process • response to drug • response to oleic acid • regulation of lipid metabolic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


2180


14081


ENSG00000151726


ENSMUSG00000018796


P33121


P41216

RefSeq (mRNA)


NM_001286708 NM_001286710 NM_001286711 NM_001286712 NM_001995


NM_007981 NM_001302163

RefSeq (protein)


NP_001273637 NP_001273639 NP_001273640 NP_001273641 NP_001986


NP_001289092 NP_032007

Location (UCSC)

PubMed search

Long-chain-fatty-acid—CoA ligase 1 is an enzyme that in humans is encoded by the ACSL1 gene.