ADH1C

ADH1C
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1HT0, 1U3W
Identifiers
Aliases	ADH1C, ADH3, alcohol dehydrogenase 1C (class I), gamma polypeptide
External IDs	MGI: 87921 HomoloGene: 73888 GeneCards: ADH1C
Gene ontology Molecular function • oxidoreductase activity • zinc ion binding • alcohol dehydrogenase (NAD) activity • metal ion binding • retinol dehydrogenase activity • alcohol dehydrogenase activity, zinc-dependent Cellular component • cytoplasm • nucleoplasm • cytosol • plasma membrane Biological process • oxidation-reduction process • ethanol oxidation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	126	11522
Ensembl	ENSG00000248144	ENSMUSG00000074207
UniProt	P00326	P00329
RefSeq (mRNA)	NM_000669	NM_007409
RefSeq (protein)	NP_000660	NP_031435.1
Location (UCSC)	Chr 4: 99.34 – 99.35 Mb	Chr 3: 138.26 – 138.29 Mb
PubMed search

1HT0, 1U3W

126

11522

ENSG00000248144

ENSMUSG00000074207

P00326

P00329

NM_000669

NM_007409

NP_000660

NP_031435.1

Alcohol dehydrogenase 1C is an enzyme that in humans is encoded by the ADH1C gene.

This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.

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Wikipedia