ANGPT2

ANGPT2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Z3S, 1Z3U, 2GY7, 4JZC, 4ZFG
Identifiers
Aliases	ANGPT2, AGPT2, ANG2, angiopoietin 2
External IDs	MGI: 1202890 HomoloGene: 22401 GeneCards: ANGPT2
Gene ontology Molecular function • metal ion binding • receptor binding • protein binding • receptor tyrosine kinase binding Cellular component • cell projection • nucleus • plasma membrane • extracellular region • extracellular space Biological process • angiogenesis • response to hypoxia • response to mechanical stimulus • negative regulation of positive chemotaxis • response to radiation • negative regulation of cell-substrate adhesion • signal transduction • animal organ regeneration • response to activity • Tie signaling pathway • cellular response to growth factor stimulus • multicellular organism development • maternal process involved in female pregnancy • negative regulation of angiogenesis • response to organic cyclic compound • leukocyte migration • negative regulation of blood vessel endothelial cell migration • blood vessel morphogenesis • germ cell development • positive regulation of angiogenesis • response to glucose • cell differentiation • glomerulus vasculature development Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	285	11601
Ensembl	ENSG00000091879	ENSMUSG00000031465
UniProt	O15123	O35608
RefSeq (mRNA)	NM_001147 NM_001118887 NM_001118888	NM_007426
RefSeq (protein)	NP_001112359 NP_001112360 NP_001138	NP_031452.2 NP_031452
Location (UCSC)	Chr 8: 6.5 – 6.56 Mb	Chr 8: 18.69 – 18.74 Mb
PubMed search

1Z3S, 1Z3U, 2GY7, 4JZC, 4ZFG

285

11601

ENSG00000091879

ENSMUSG00000031465

O15123

O35608

NM_001147
NM_001118887
NM_001118888

NM_007426

NP_001112359
NP_001112360
NP_001138

NP_031452.2
NP_031452

Angiopoietin-2 is a protein that in humans is encoded by the ANGPT2 gene.

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