ARHGEF1

ARHGEF1

Protein ARHGEF1 PDB 1iap.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1IAP, 1SHZ, 3AB3, 3ODO, 3ODW, 3ODX, 3P6A

Identifiers

ARHGEF1, GEF1, LBCL2, LSC, P115-RHOGEF, SUB1.5, Rho guanine nucleotide exchange factor 1

External IDs

MGI: 1353510 HomoloGene: 3454 GeneCards: ARHGEF1

Gene ontology
Molecular function	• Rho guanyl-nucleotide exchange factor activity • protein binding • GTPase activator activity • RNA binding • guanyl-nucleotide exchange factor activity
Cellular component	• plasma membrane • membrane • cytoplasm • cytosol
Biological process	• negative regulation of axonogenesis • cell proliferation • regulation of Rho protein signal transduction • Rho protein signal transduction • positive regulation of GTPase activity • positive regulation of apoptotic process • regulation of small GTPase mediated signal transduction
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE ARHGEF1 203055 s at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


9138


16801


ENSG00000076928


ENSMUSG00000040940


Q92888


Q61210

RefSeq (mRNA)


NM_004706 NM_198977 NM_199002


NM_001130150 NM_001130151 NM_001130152 NM_001130153 NM_008488

RefSeq (protein)


NP_004697 NP_945328 NP_945353

NP_001123622.1 NP_001123623.1 NP_001123624.1 NP_001123625.1 NP_032514.1
NP_001123622 NP_001123623 NP_001123624 NP_001123625 NP_032514

Location (UCSC)

Chr 19: 41.88 – 41.93 Mb

Chr 7: 24.9 – 24.93 Mb

PubMed search

1IAP, 1SHZ, 3AB3, 3ODO, 3ODW, 3ODX, 3P6A

ENSG00000076928

ENSMUSG00000040940

NM_004706
NM_198977
NM_199002

NM_001130150
NM_001130151
NM_001130152
NM_001130153
NM_008488

NP_004697
NP_945328
NP_945353

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Wikipedia

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