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Angiopoietin-related protein 1

ANGPTL1
Identifiers
Aliases ANGPTL1, ANG3, ANGPT3, ARP1, AngY, UNQ162, dJ595C2.2, angiopoietin like 1
External IDs MGI: 1919963 HomoloGene: 128467 GeneCards: ANGPTL1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004673

NM_028333

RefSeq (protein)

NP_004664

NP_082609.2
NP_082609

Location (UCSC) Chr 1: 178.85 – 178.87 Mb Chr 1: 156.84 – 156.86 Mb
PubMed search

NM_004673

NM_028333

NP_004664

NP_082609.2
NP_082609

Angiopoietin-related protein 1 also known as angiopoietin-3 (ANG-3) is a protein that in humans is encoded by the ANGPTL1 gene.

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels.

The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro.


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