Antazoline

Antazoline

Clinical data
Trade names	Vasocon-a
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of administration	Topical (nasal, eye drops)
ATC code	R01AC04 (WHO) R06AX05 (WHO)
Identifiers
IUPAC name N-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-N-(phenylmethyl)aniline
CAS Number	91-75-8 Y
PubChem CID	2200
IUPHAR/BPS	7116
DrugBank	DB08799 Y
ChemSpider	2115 Y
UNII	DHA8014SS1
KEGG	D07458 Y
ChEBI	CHEBI:84115 N
ChEMBL	CHEMBL1305 Y
ECHA InfoCard	100.001.904
Chemical and physical data
Formula	C17H19N3
Molar mass	265.353 g/mol
3D model (Jmol)	Interactive image
SMILES N\1=C(\NCC/1)CN(c2ccccc2)Cc3ccccc3
InChI InChI=1S/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16/h1-10H,11-14H2,(H,18,19) Y Key:REYFJDPCWQRWAA-UHFFFAOYSA-N Y
NY (what is this?)

Antazoline is a 1st generation antihistamine with anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis. The drug is a Histamine H1 receptor antagonist: selectively binding to but not activating the receptor, thereby blocking the actions of endogenous histamine and subsequently leading to the temporary relief of the negative symptoms brought on by histamine.