Aquaporin-1

AQP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4CSK, 1FQY, 1H6I, 1IH5
Identifiers
Aliases	AQP1, AQP-CHIP, CHIP28, CO, aquaporin 1 (Colton blood group)
External IDs	OMIM: 107776 MGI: 103201 HomoloGene: 68051 GeneCards: AQP1
Gene location (Human) Chr. Chromosome 7 (human) Band 7p14.3 Start 30,911,694 bp End 30,925,516 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6 B3|6 27.38 cM Start 55,336,432 bp End 55,348,555 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • transporter activity • ammonium transmembrane transporter activity • nitric oxide transmembrane transporter activity • intracellular cGMP activated cation channel activity • potassium channel activity • transmembrane transporter activity • carbon dioxide transmembrane transporter activity • protein binding • water transmembrane transporter activity • potassium ion transmembrane transporter activity • glycerol transmembrane transporter activity • water channel activity • ephrin receptor binding Cellular component • cytoplasm • nuclear membrane • symbiont-containing vacuole membrane • membrane • nucleus • apical plasma membrane • integral component of membrane • plasma membrane • apical part of cell • basal plasma membrane • integral component of plasma membrane • brush border membrane • basolateral plasma membrane • sarcolemma • brush border • symbiont-containing vacuole • axon • neuron projection • axon terminus • extracellular exosome Biological process • cellular response to retinoic acid • ammonium transport • cellular response to mechanical stimulus • cellular response to copper ion • cellular response to nitric oxide • cellular response to hypoxia • cellular response to cAMP • carbon dioxide transmembrane transport • positive regulation of fibroblast proliferation • cellular homeostasis • pancreatic juice secretion • cGMP biosynthetic process • cellular response to stress • cellular response to salt stress • cellular response to inorganic substance • cell volume homeostasis • cellular response to UV • establishment or maintenance of actin cytoskeleton polarity • negative regulation of apoptotic process • cellular response to dexamethasone stimulus • positive regulation of angiogenesis • odontogenesis • renal water transport • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • cellular response to mercury ion • nitric oxide transport • cellular hyperosmotic response • bicarbonate transport • positive regulation of saliva secretion • renal water homeostasis • multicellular organismal water homeostasis • transepithelial water transport • response to drug • carbon dioxide transport • cellular response to hydrogen peroxide • cerebrospinal fluid secretion • potassium ion transmembrane transport • ammonium transmembrane transport • cation transmembrane transport • glomerular filtration • potassium ion transport • water transport • hyperosmotic response • response to hormone • positive regulation of lamellipodium assembly • positive regulation of epithelial cell migration • glycerol transport • sensory perception of pain • lateral ventricle development • water homeostasis • positive regulation of cell migration • secretion by cell • secretory granule organization • wound healing • hyperosmotic salinity response • response to estrogen • lipid digestion • camera-type eye morphogenesis • corticotropin secretion • renal water absorption • metanephric descending thin limb development • metanephric proximal straight tubule development • metanephric proximal convoluted tubule segment 2 development • metanephric glomerulus vasculature development • maintenance of symbiont-containing vacuole by host • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	358	11826
Ensembl	ENSG00000240583	ENSMUSG00000004655
UniProt	P29972 Q6JSD8 Q6JSD7	Q02013
RefSeq (mRNA)	NM_198098 NM_000385 NM_001185060 NM_001185061 NM_001185062 NM_001329872	NM_007472
RefSeq (protein)	NP_001171989 NP_001171990 NP_001171991 NP_001316801 NP_932766	NP_031498
Location (UCSC)	Chr 7: 30.91 – 30.93 Mb	Chr 7: 55.34 – 55.35 Mb
PubMed search

4CSK, 1FQY, 1H6I, 1IH5

358

11826

ENSG00000240583

ENSMUSG00000004655

P29972
Q6JSD8
Q6JSD7

Q02013

NM_001329872

NM_007472

NP_001171989
NP_001171990
NP_001171991
NP_001316801
NP_932766

NP_031498

Aquaporin 1 is a protein that in humans is encoded by the AQP1 gene.

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