Archagathus (Greek: Ἀρχάγαθος) was a Syracusan Greek prince and Ptolemaic official who lived around the late second half of the 4th century BC and first half of the 3rd century BC.
Archagathus was a man of Sicilian origin and his name was a well-attested local Greek name in Sicily. He was the son born to Agathocles and his third wife Theoxena and had a sister called Theoxena.
His father Agathocles was a Greek Tyrant of Syracuse who later became King of Sicily. Archagathus had two paternal-half posthumous brothers: Archagathus and Agathocles; one paternal half-sister Lanassa who was the second wife of King Pyrrhus of Epirus and a posthumous paternal half-nephew Archagathus. He was the namesake of his posthumous brother, nephew and possibly his paternal grandfather.
His mother Theoxena was a Greek Macedonian noblewoman. She was the second daughter and third child born to the noblewoman Berenice I and her first husband obscure nobleman Philip. Archagathus’ biological maternal grandfather Philip, served as a military officer in the service of the Greek King Alexander the Great and was known in commanding one division of the Phalanx in Alexander’s wars. Archagathus’ maternal grandmother Berenice I, was the great-niece of the powerful Regent Antipater and she was a distant collateral relative to the Argead dynasty. His full blooded maternal uncle was Magas of Cyrene and his full-blooded maternal aunt was Antigone.