Arginylglycylaspartic acid

Arginylglycylaspartic acid

Names
Systematic IUPAC name (2S)-2-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]butanedioic acid
Other names L-Arginyl-Glycyl-L-Aspartic acid; Arg-Gly-Asp
Identifiers
CAS Number	99896-85-2 Y
3D model (JSmol)	Interactive image
Abbreviations	RGD Peptide
ChemSpider	2575945 N 94603 N
MeSH	arginyl-glycyl-aspartic+acid
PubChem CID	3328704 104802
InChI InChI=1S/C12H22N6O6/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16) N Key: IYMAXBFPHPZYIK-UHFFFAOYSA-N N
SMILES C(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)O)N)CN=C(N)N
Properties
Chemical formula	C12H22N6O6
Molar mass	346.34 g·mol−1
log P	−3.016
Acidity (pKa)	2.851
Basicity (pKb)	11.146
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

Arginylglycylaspartic acid (RGD) is a tripeptide composed of L-arginine, glycine, and L-aspartic acid. The sequence is a common element in cellular recognition. Arginylglycylaspartic acid is used as a biochemical tool in the study of this recognition.

RGD-peptides are implicated in cellular attachment via integrins, and can be used to coat synthetic scaffolds in tissue engineering to enhance cellular attachment by mimicking in vivo conditions.