Arthur Horwich
| Arthur L. Horwich | |
|---|---|
| Born | 1951 |
| Residence | United States |
| Nationality | American |
| Fields | Biology |
| Institutions |
Yale School of Medicine Howard Hughes Medical Institute |
| Alma mater | Brown University |
| Known for | uncovering chaperonin action |
| Notable awards |
Hans Neurath Award, Protein Society (2001) Gairdner Foundation International Award (2004) Stein and Moore Award, Protein Society (2006) Wiley Prize in Biomedical Science (2007) Rosenstiel Award (2008) Louisa Gross Horwitz Prize (2008) Lasker Award (2011) Shaw Prize (2012) |
Arthur L. Horwich (born 1951) is an American biologist and Sterling Professor of Genetics and Pediatrics at the Yale School of Medicine. Horwich has also been a Howard Hughes Medical Institute investigator since 1990. His research into protein folding uncovered the action of chaperonins, protein complexes that assist the folding of other proteins. Horwich first published this work in 1989.
Horwich was born in 1951. He grew up in Oak Park, west of Chicago. In 1969, he entered Brown University as part of the Program in Liberal Medical Education, a new program that combined the undergraduate degree with medical school. During medical school, Horwich studied fat cell metabolism in the laboratory of John Fain. Horwich received his A.B. in biomedical sciences in 1972 and his M.D. in 1975. He graduated as valedictorian of the first class to complete the combined program. Horwich went on to do an internship and residency in pediatrics at Yale University. Midway through, Horwich was not sure about an entirely clinical future. After completing his residency, he joined the Salk Institute for Biological Studies in La Jolla, California for a postdoctoral position in molecular biology and virology. At Salk, he worked in Walter Eckhart's laboratory alongside Tony Hunter and witnessed Hunter's discovery of tyrosine phosphorylation. He credits this time with sharpening his skills as a scientist. He said, "Tony taught me the nuts and bolts of thinking about a problem."
In 1981, Horwich moved back to New Haven, Connecticut for a postdoctoral fellowship at Yale University School of Medicine. He worked in the laboratory of Leon Rosenberg.
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