The men's 110 metres hurdles event at the 2007 Pan American Games was held on July 27–28.
Qualification: First 2 of each heat (Q) and the next 2 fastest (q) qualified for the final.
Wind:
Heat 1: +0.1 m/s, Heat 2: -0.2 m/s, Heat 3: +0.4 m/s
Wind: +0.4 m/s