BMPR1A

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3QB4, 1ES7, 1REW, 2GOO, 2H62, 2H64, 2K3G, 2QJ9, 2QJA, 2QJB, 3NH7

Identifiers

Aliases

BMPR1A, 10q23del, ACVRLK3, ALK3, CD292, SKR5, bone morphogenetic protein receptor type 1A

External IDs

OMIM: 601299 MGI: 1338938 HomoloGene: 20911 GeneCards: BMPR1A

Gene ontology
Molecular function	• transferase activity • nucleotide binding • protein kinase activity • signal transducer, downstream of receptor, with serine/threonine kinase activity • protein homodimerization activity • glycoprotein binding • metal ion binding • kinase activity • protein serine/threonine kinase activity • transmembrane receptor protein serine/threonine kinase activity • protein binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding • SMAD binding • ATP binding • BMP receptor activity
Cellular component	• integral component of membrane • HFE-transferrin receptor complex • membrane • plasma membrane • neuronal cell body • dendrite • caveola • external side of plasma membrane
Biological process	• somitogenesis • pattern specification process • palate development • cell differentiation • pituitary gland development • endoderm development • chondrocyte differentiation • neural crest cell development • signal transduction by protein phosphorylation • lateral mesoderm development • lung development • positive regulation of bone mineralization • embryonic organ development • paraxial mesoderm structural organization • positive regulation of epithelial cell proliferation • phosphorylation • negative regulation of neurogenesis • positive regulation of pathway-restricted SMAD protein phosphorylation • mesoderm formation • ectoderm development • embryonic digit morphogenesis • heart morphogenesis • cellular response to BMP stimulus • in utero embryonic development • BMP signaling pathway • hindlimb morphogenesis • nervous system development • dorsal/ventral axis specification • regulation of lateral mesodermal cell fate specification • stem cell population maintenance • odontogenesis of dentin-containing tooth • Mullerian duct regression • endocardial cushion formation • protein phosphorylation • positive regulation of transcription, DNA-templated • heart development • cartilage development • positive regulation of osteoblast differentiation • developmental growth • transmembrane receptor protein serine/threonine kinase signaling pathway • positive regulation of mesenchymal cell proliferation • heart formation • neural plate pattern specification • embryonic morphogenesis • mesendoderm development • immune response • regulation of cellular senescence • neural plate mediolateral regionalization • dorsal/ventral pattern formation • transforming growth factor beta receptor signaling pathway • positive regulation of SMAD protein import into nucleus • anterior/posterior pattern specification • paraxial mesoderm development • positive regulation of pri-miRNA transcription from RNA polymerase II promoter • negative regulation of smooth muscle cell migration • BMP signaling pathway involved in heart development • regulation of cardiac muscle cell apoptotic process • outflow tract septum morphogenesis • outflow tract morphogenesis • cardiac conduction system development • mitral valve morphogenesis • tricuspid valve morphogenesis • endocardial cushion morphogenesis • cardiac right ventricle morphogenesis • ventricular trabecula myocardium morphogenesis • ventricular compact myocardium morphogenesis • dorsal aorta morphogenesis • positive regulation of transcription from RNA polymerase II promoter • regulation of cardiac muscle cell proliferation • positive regulation of cardiac muscle cell proliferation • pharyngeal arch artery morphogenesis • positive regulation of cardiac ventricle development • positive regulation of vascular smooth muscle cell proliferation • fibrous ring of heart morphogenesis • regulation of neural crest cell differentiation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


657


12166

Ensembl


ENSG00000107779


ENSMUSG00000021796

UniProt


P36894


P36895

RefSeq (mRNA)


NM_004329


NM_009758

RefSeq (protein)


NP_004320


NP_033888.2 NP_033888

Location (UCSC)

Chr 10: 86.76 – 86.93 Mb

Chr 14: 34.41 – 34.5 Mb

PubMed search

3QB4, 1ES7, 1REW, 2GOO, 2H62, 2H64, 2K3G, 2QJ9, 2QJA, 2QJB, 3NH7

NP_033888.2
NP_033888

...
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