The Metropolis of Pergamon (Greek: Μητρόπολις Περγάμου) was an ecclesiastical territory (diocese) of the Ecumenical Patriarchate of Constantinople in western Asia Minor, modern Turkey. Christianity in the city of Pergamon (modern Bergama), was introduced already from 1st century AD, while the local Christian community comprised one of the seven Churches of Asia mentioned at the Book of Revelation, written by John of Patmos. The bishopric of Pergamon was twice promoted to a metropolis: during the 13th–14th centuries, as well as for a short period in 1922. Today the Metropolis of Pergamon and Adramyttium is the see of a titular metropolitan.
The Christian community of Pergamon was one of the earliest established in Asia Minor during the 1st century AD. It also comprised one of the Seven Churches of Asia mentioned at the New Testament Book of Revelation, written by John the Apostle. According to the Christian tradition, Antipas was appointed bishop of Pergamon, by John. He martyred there at 92 AD. Pergamon became the see of a bishopric under the jurisdiction of the Metropolis of Ephesus. During the 13th century the local bishopric was promoted to a metropolis. However, it soon ceased to exist as a result of the Turkish conquest of the area in the 1310s, the subsequent decline of the local Christian population and the later destruction of Pergamon by the hordes of Timur. Thus, during the following centuries, the region became again part of the wider Metropolis of Ephesus.