Brandon Eric Guyer (born January 28, 1986) is an American professional baseball outfielder for the Cleveland Indians of Major League Baseball (MLB). He previously played for the Tampa Bay Rays. His knack for getting hit by pitches has earned the nickname, "La Piñata."

Guyer is a 2004 graduate of Herndon High School where he was a three-year letter winner in baseball as well as football. In football, he rushed for over 1,000 yards as a tailback for the Hornets in both his junior and senior seasons. As a senior, he set the school single-game touchdown record, scoring seven touchdowns during a 285-yard rushing performance on homecoming night (October 4, 2003, Herndon 44, West Potomac 26). Guyer helped Herndon break a six-year Northern Region playoff drought, leading the Hornets to a 7-4 season. He was a third team all-state pick as a junior and a second team all-state pick as a senior. In baseball, Guyer is the Hornets' all-time career home run hitter (13) and holds the single-season home run record with eight. He was a part of the Hornets 19-4 Concorde District championship squad in 2002—the last time Herndon won a district title. As a senior, he had 23 RBI, a .483 batting average and was walked 19 times.

Guyer attended the University of Virginia, and played college baseball for the Virginia Cavaliers baseball team. He was drafted by the Chicago Cubs in the 2007 amateur draft.

After the 2010 season, Guyer was included in a trade to the Tampa Bay Rays with Hak-Ju Lee, Chris Archer, Robinson Chirinos and Cubs outfielder Sam Fuld for Matt Garza, Fernando Perez and Zac Rosscup.

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