CCR10

CCR10
Identifiers
Aliases	CCR10, GPR2, C-C motif chemokine receptor 10
External IDs	MGI: 1096320 HomoloGene: 7271 GeneCards: CCR10
Gene ontology Molecular function • C-C chemokine receptor activity • G-protein coupled receptor activity • chemokine receptor activity • signal transducer activity • protein binding Cellular component • cell surface • integral component of membrane • plasma membrane • integral component of plasma membrane • membrane Biological process • positive regulation of cytosolic calcium ion concentration • chemotaxis • chemokine-mediated signaling pathway • G-protein coupled receptor signaling pathway • immune response • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2826	12777
Ensembl	ENSG00000184451	ENSMUSG00000044052
UniProt	P46092	Q9JL21
RefSeq (mRNA)	NM_016602	NM_007721
RefSeq (protein)	NP_057686	NP_031747.2 NP_031747
Location (UCSC)	Chr 17: 42.68 – 42.68 Mb	Chr 11: 101.17 – 101.18 Mb
PubMed search

2826

12777

ENSG00000184451

ENSMUSG00000044052

P46092

Q9JL21

NM_016602

NM_007721

NP_057686

NP_031747.2
NP_031747

C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene.

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines.

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Wikipedia