CIRBP

CIRBP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1X5S
Identifiers
Aliases	CIRBP, CIRP, cold inducible RNA binding protein
External IDs	MGI: 893588 HomoloGene: 980 GeneCards: CIRBP
Gene ontology Molecular function • translation repressor activity • nucleic acid binding • protein binding • small ribosomal subunit rRNA binding • mRNA 3'-UTR binding • RNA binding Cellular component • cytoplasm • cytoplasmic stress granule • nucleolus • nucleus • nucleoplasm Biological process • stress granule assembly • response to cold • mRNA stabilization • response to UV • positive regulation of translation • negative regulation of translation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1153	12696
Ensembl	ENSG00000099622	ENSMUSG00000045193
UniProt	Q14011 Q53XX5	P60824
RefSeq (mRNA)	NM_001280 NM_001300815 NM_001300829	NM_007705
RefSeq (protein)	NP_001271 NP_001287744 NP_001287758 NP_001271.1	NP_031731.1 NP_031731
Location (UCSC)	Chr 19: 1.26 – 1.27 Mb	Chr 10: 80.17 – 80.17 Mb
PubMed search

1X5S

1153

12696

ENSG00000099622

ENSMUSG00000045193

Q14011
Q53XX5

P60824

NM_001280
NM_001300815
NM_001300829

NM_007705

NP_001271
NP_001287744
NP_001287758
NP_001271.1

NP_031731.1
NP_031731

Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene. The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia.

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Wikipedia