CNBP gene

CNBP
Identifiers
Aliases	CNBP, CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9, CCHC-type zinc finger nucleic acid binding protein
External IDs	MGI: 88431 HomoloGene: 2567 GeneCards: CNBP
Gene location (Human) Chr. Chromosome 3 (human) Band n/a Start 129,169,484 bp End 129,183,922 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band n/a Start 87,842,615 bp End 87,851,106 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • protein binding • nucleic acid binding • zinc ion binding • transcription factor activity, sequence-specific DNA binding • metal ion binding • DNA binding • single-stranded DNA binding • single-stranded RNA binding • RNA binding • RNA polymerase II regulatory region sequence-specific DNA binding • transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding Cellular component • nucleus • cytoplasm • endoplasmic reticulum • cytosol Biological process • regulation of transcription, DNA-templated • cholesterol biosynthetic process • transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • positive regulation of transcription, DNA-templated • positive regulation of cell proliferation • negative regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7555	12785
Ensembl	ENSG00000169714	ENSMUSG00000030057
UniProt	P62633	P53996
RefSeq (mRNA)	NM_003418 NM_001127192 NM_001127193 NM_001127194 NM_001127195 NM_001127196	NM_001109745 NM_001109746 NM_013493 NM_001347325
RefSeq (protein)	NP_001120664 NP_001120665 NP_001120666 NP_001120667 NP_001120668 NP_003409	NP_001103215 NP_001103216 NP_001334254 NP_038521
Location (UCSC)	Chr 3: 129.17 – 129.18 Mb	Chr 3: 87.84 – 87.85 Mb
PubMed search

7555

12785

ENSG00000169714

ENSMUSG00000030057

P62633

P53996

NM_001127196

NM_001109745
NM_001109746
NM_013493
NM_001347325

NP_003409

NP_001103215
NP_001103216
NP_001334254
NP_038521

Cellular nucleic acid-binding protein is a protein that in humans is encoded by the CNBP gene.

The ZNF9 protein contains 7 zinc finger domains and is believed to function as an RNA-binding protein. A CCTG expansion in intron 1 of the ZNF9 gene results in myotonic dystrophy type 2 (MIM 602668).[supplied by OMIM]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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