The CSX Saginaw Subdivision is a railroad line in the U.S. state of Michigan. The line runs 105 miles from Toledo, Ohio to Saginaw, Michigan; although since 2006, the section from Mt. Morris to Saginaw has been leased to the Lake State Railway, but is still occasionally used by CSX.
Before CSX Transportation operated trains on the Saginaw Subdivision, it was originally owned by the Pere Marquette Railway. In the year 1947, the PM was acquired by the Chesapeake and Ohio Railway. It continued under the control of the C&O until 1973 upon which the Chessie System assumed operations of the line. In 1980, when the Chessie System merged with the Seaboard Air Line and the Louisville and Nashville Railroad, the line became owned by its current owner, CSX. Over the years the line has lost a lot of traffic and many of the industrial spurs have since been abandoned. The Flint and Holly Railroad was built by Henry Howland Crapo in the 1860s to serve his lumber mill. A park near the junction of Canadian National Railway's Holly Subdivision (a branch line of the old Grand Trunk Western Railroad), is named for him and a Michigan Historical Marker about him and the railroad's section stands there.
The line begins in Toledo, Ohio where it connects with the Toledo Terminal Division. Heading north, the line comes into the village of Carleton, Michigan. In Carleton, the Conrail Lincoln Secondary branches off and the Canadian National Railway's Flat Rock Subdivision crosses. Continuing onto Wayne, Michigan, the line crosses the Michigan Line, operated by Amtrak. CSX trains can interchange with NS here. There is a Ford automobile plant, which requires autorack cars for loading. North of Wayne, it enters Plymouth, Michigan. At Plymouth Diamond (MP CH82), the Saginaw Subdivision meets the east-west CSX Plymouth Subdivision-Detroit Subdivision line.