Calponin 1, basic, smooth muscle

CNN1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WYP
Identifiers
Aliases	CNN1, HEL-S-14, SMCC, Sm-Calp, calponin 1
External IDs	MGI: 104979 HomoloGene: 995 GeneCards: CNN1
Gene location (Human) Chr. Chromosome 19 (human) Band 19p13.2 Start 11,538,717 bp End 11,550,323 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 A3 Start 22,099,216 bp End 22,109,630 bp
Gene ontology Molecular function • actin binding • calmodulin binding • protein binding Cellular component • cytoskeleton • focal adhesion Biological process • actomyosin structure organization • regulation of smooth muscle contraction • negative regulation of vascular smooth muscle cell proliferation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	1264	12797
Ensembl	ENSG00000130176	ENSMUSG00000001349
UniProt	P51911	Q08091
RefSeq (mRNA)	NM_001299 NM_001308341 NM_001308342	NM_009922
RefSeq (protein)	NP_001290 NP_001295270 NP_001295271	NP_034052
Location (UCSC)	Chr 19: 11.54 – 11.55 Mb	Chr 19: 22.1 – 22.11 Mb
PubMed search

1WYP

1264

12797

ENSG00000130176

ENSMUSG00000001349

P51911

Q08091

NM_001299
NM_001308341
NM_001308342

NM_009922

NP_001290
NP_001295270
NP_001295271

NP_034052

Calponin 1 is a basic smooth muscle protein that in humans is encoded by the CNN1 gene.

The CNN1 gene is located at 19p13.2-p13.1 in the human chromosomal genome and contains 7 exons, encoding the protein calponin 1, an actin filament-associated regulatory protein. Human calponin 1 is a 33.2-KDa protein consists of 297 amino acids with an isoelectric point of 9.1, thus calponin 1 is also known as basic calponin.

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