Cardinal René de Prie

René de Prie (1451–1519) was a French Roman Catholic bishop and cardinal.

René de Prie was born in Touraine in 1451, the son of Antoine de Prie, baron of Buzançais, and Madeleine d'Amboise. He was a cousin of Cardinal Georges d'Amboise.

Through the influence of his cousin the cardinal, Prie became grand-archdeacon of Bourges; archdeacon of Blois; and dean of the Église Saint-Hilaire-le-Grand. He was also a protonotary apostolic.

On August 3, 1498, he was elected Bishop of Bayeux. He entered his see on March 25, 1499 and occupied it until November 24, 1516.

On January 8, 1499, in Nantes, he signed the marriage contract of Louis XII of France and Anne of Brittany. Louis XII then sent him to Étaples to conclude a treaty with Henry VII of England. He became prior of Layrac. During the Italian War of 1499–1504, he accompanied Louis XII to Genoa. On May 20, 1506, the king gave him the title of baron of Précigné and the abbey of Déols.

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