Cathepsin C

CTSC

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4OEM, 1K3B, 2DJF, 2DJG, 3PDF, 4CDC, 4CDD, 4CDE, 4CDF, 4OEL

Identifiers

Aliases

CTSC, CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS, cathepsin C

External IDs

OMIM: 602365 MGI: 109553 HomoloGene: 1373 GeneCards: CTSC

Gene ontology
Molecular function	• peptidase activator activity involved in apoptotic process • phosphatase binding • cysteine-type peptidase activity • chaperone binding • protein self-association • peptidase activity • protein binding • identical protein binding • chloride ion binding • cysteine-type endopeptidase activity • serine-type endopeptidase activity • hydrolase activity
Cellular component	• Golgi apparatus • endoplasmic reticulum lumen • membrane • endoplasmic reticulum • ER to Golgi transport vesicle • lysosome • extracellular exosome • endoplasmic reticulum-Golgi intermediate compartment membrane • Golgi membrane • extracellular region • extracellular space • nucleoplasm • centrosome • azurophil granule lumen • intracellular membrane-bounded organelle
Biological process	• aging • positive regulation of proteolysis involved in cellular protein catabolic process • positive regulation of apoptotic signaling pathway • response to organic substance • proteolysis • ER to Golgi vesicle-mediated transport • COPII vesicle coating • immune response • proteolysis involved in cellular protein catabolic process • T cell mediated cytotoxicity • apoptotic process • neutrophil degranulation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


1075


13032

Ensembl


ENSG00000109861


ENSMUSG00000030560

UniProt


P53634


P97821

RefSeq (mRNA)


NM_148170 NM_001114173 NM_001814


NM_009982 NM_001311790

RefSeq (protein)


NP_001107645 NP_001805 NP_680475


NP_034112.3 NP_001298719 NP_034112

Location (UCSC)

Chr 11: 88.29 – 88.34 Mb

Chr 7: 88.28 – 88.31 Mb

PubMed search

Cathepsin C exclusion domain

re-determination of the native structure of human dipeptidyl peptidase i (cathepsin c)

Identifiers

Symbol

CathepsinC_exc

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

4OEM, 1K3B, 2DJF, 2DJG, 3PDF, 4CDC, 4CDD, 4CDE, 4CDF, 4OEL

NM_148170
NM_001114173
NM_001814

NM_009982
NM_001311790

NP_001107645
NP_001805
NP_680475

...
Wikipedia